Learning objectives:

Our experts will answer the following questions:
1. Is endoscopic surveillance still indicated for patients with Barrett's esophagus?
2. When is endoscopic surveillance not needed and how to safely discontinue?
3. What are best practices for enhanced neoplasia detection, including the use of high-definition white-light endoscopy, structured biopsy sampling, and expert pathology review?
4. Why is daily proton pump inhibitor (PPI) therapy preferred over no PPI and over anti-reflux surgery?
5. How should clinicians use advanced sampling techniques and biomarkers?
6. What do we not know yet (key evidence gaps and research priorities)?